Hiv Pre-Exposure Prophylaxis (PrEp)

Posted by | Posted in Hiv Infection Articles | Posted on 16-02-2012

The most basic request to ask is “What is Hiv pre-exposure prophylaxis (PrEp)?”

Pre-exposure prophylaxis is any treatment you take to preclude catching a disease before you get exposure to it. So, you take this treatment to preclude catching an Hiv infection, before you get exposure to the virus. This treatment protocol uses antiretroviral drugs used in treating Hiv infections. The drugs that researchers are testing are tenofovir and emtricitabine in a combined tablet. Studies, done in animal models, demonstrated that this compound was very sufficient for preventing infection. A huuman trial performed last year also demonstrated that this compound was able to cut down on potential infections. The median discount was 42 percent (range: 15 to 65 percent agreeing to cases).

What is required for Hiv pre-exposure prophylaxis (PrEp) to work effectively?

One dissimilarity in the middle of the animal and human studies is the fact that human beings are not in cages and closely monitored. The human trials involve giving the medications to high-risk groups and having them record for testing every few weeks. Test subjects who stuck with the drug protocol closely had more security than those that did not result the protocol closely. So, in order for this to work, those taking the drugs must closely result protocols in order to get the most result from it. They were also advised to systematically use condoms, and these arresting measures were assessed and repeated at each protocol visit.

Which groups would advantage from Hiv pre-exposure prophylaxis (PrEp)?

The safest method for preventing transmission of the Hiv virus involves not having unprotected sex or not sharing used drug needles. The pre-exposure prophylaxis can be seen as an additional portion of prevention. Some have suggested it would work for couples who want to conceive children when one partner is Hiv sure and the other one is not. Someone else use would be among women who have no choice on insisting their partners use condoms. Because the PrEp is not 100% effective, this should be a secondary arresting measure.

What are base concerns about the use of Hiv pre-exposure prophylaxis (PrEp)?

In the Us, Aids organizations have expressed concerns that using PrEp would potentially give a false sense of safety. This might lead to lower usage of condoms among high-risk populations. Someone else concern raised is the fact that using the drug before an infection would build up drug resistance in case of infection in the future. There are ethical concerns about how the drug testing goes on among high-risk populations. These concerns consist of the use of a placebo with a deadly disease and the lack of counseling trial patients receive in some locations. The PrEp may be a step in the right direction, but it is not the excellent answer.

Finally, Someone else ethical concern is production ready antiretroviral drugs for arresting to uninfected peopulations who can afford them, although millions of infected patients around the world cannot afford this therapy!



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Hiv & Aids – Ayurvedic Herbal Treatment, an modernize

Posted by | Posted in Hiv Infection Articles | Posted on 25-01-2012

Hiv infection is a medical health characterized by a progressive deficiency in the immune law of the human body, caused by the Human Immunodeficiency Virus. Currently there is no cure for this condition. However, anti-retroviral therapy has succeeded in reducing the virus count to a bare minimum, and has helped the immune law to improve. This therapy has many side-effects, and over time, the virus starts multiplying, while the immune law fails gradually.

Some Ayurvedic physicians compare the symptoms of Hiv/Aids to those of “Kshaya” or “Oja-Kshaya” mentioned in Ayurveda. While Ayurvedic medicine may not show the initial dramatic revision seen with modern drugs, this medicine still has a essential role to play in the long term administration of Hiv infection. Ayurvedic medicines sacrifice the virus count and heighten the Cd4/Cd8 count, which are indicative of the modulated immune status of the body. Judicious use of Ayurvedic medicines may also increase the innate (basic) immunity of the body, heighten weight and cause urination of the Hiv virus from the body.

Traditional Ayurvedic formulations can be effectively used to treat the opportunistic infections which are a hallmark of advanced Hiv infection. Kutaj Ghana Vati, Sanjeevani Vati, Panchamrut Parpati and Kutaj Parpati are used to treat recurrent diarrhea. Arogya Vardhini, Triphala Guggulu, Mahamanjishthadi Ghan Vati, Praval and Kamdudha are useful in Herpes Zoster infection and also in other skin infections. Laxmi Narayan Rasa, Samshamani Vati and Laghu Sutshekhar are used in continuing fever. Chandanadi Vati, Shatadhout Ghrut,Yashtimadhuk Ghrut, Triphala and Chandan (Sandalwood ) powders are useful in recurrent oral and genital ulcers. Laghu Malini Vasant, Madhu Malini Vasant, Suvarna Malini Vasant, Suvarna Bhasma and Heerak Bhasma are used as “general tonics”.

Herbal medicines which are useful in Hiv infection are: Amalaki (Emblica officinalis), Bhumiamalaki (Phyllanthus niruri), Yashtimadhuk (Glycerrhiza glabra), Shatavari (Asparagus racemosus), Ashwagandha (Withania somnifera), Tulsi (Ocimum sanctum), Mandukparni (Centella asiatica), Kutki (Picrorrhiza kurroa), Saariva (Hemidesmus indicus), Manjishtha (Rubia cordifolia), Haridra (Curcuma longa), Punarnava (Boerhaavia diffusa), Pippali (Piper longum) and Chitrak (Plumbago zeylanica). These medicines have anti-viral, immunomodulating and adaptogenic properties. Some of these increase body weight, yet others increase the “agni” of the body and therefore profess cellular metabolism at an optimum level.

Patients with Hiv infection need long-term or life-long treatment. Herbal medicines have the benefit of an impressive safety profile, and can therefore, be given for long periods without any essential side effects. Herbal medicines can be given independently, or as further therapy to modern medicines. The current goal in Hiv administration of prolonging a salutary life at minimum risk and cost, can thus, be achieved admirably with herbal medicines.



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